Pediatric Hereditary Angioedema (HAE) Diagnosis & Management: Challenges, Barriers, Strategies Miniseries Episode 1 – Diagnosing HAE Accurately

Host: Kristin C. Sokol, MD, MS, MPH, FACAAI

Experts: Aleena Banerji, MD; Timothy J. Craig, DO, FACAAI

This discussion covers the key factors in accurately diagnosing HAE, including clinical history, lab testing, and the role of genetic testing in distinguishing between HAE types. Special considerations for diagnosing pediatric patients will also be discussed.

Learning Objective:

After listening to this podcast episode, participants should be better able to:

• Diagnose pediatric HAE accurately

References:

1. Allen Meadows, MD; John Anderson, MD; Richard G. Gower, MD. Challenges in the management of hereditary angioedema in urban and rural settings. Results of a United States survey. Ann Allergy Asthma Immunol 130 (2023) 760−767.
2. Riedl MA, Johnston DT, Anderson J, Meadows JA, Soteres D, LeBlanc SB, etal. Optimization of care for patients with hereditary angioedema living in rural areas. Ann Allergy Asthma Immunol.2022;128(5):526–533.
3. Busse PJ, Christiansen SC, Riedl MA, Banerji A, Bernstein JA, Castaldo AJ, et al. US HAEA Medical Advisory Board 2020 guidelines for the management of hereditary angioedema. JAllergyClinImmunolPract.2021;9(1):132–150.e3
4. Mauer M, Magerl M, Bethschel A, Aberer W, et al. The international WAO/EAACI guideline for the management of hereditary angioedema—The 2021 revision and update Allergy. 10 January 2022

Speaker Disclosures:

Kristin C. Sokol, MD, MS, MPH, FACAAI

Advisor: Sanofi, Genentech, SELF/Conde Nast

 

Aleena Banerji, MD

Advisor: Astria, Biocryst, CSL Behring, Ionis, Intellia, Kalvista, Pharvaris, Takeda

Researcher: Astria, Ionis, Intellia

 

Timothy J. Craig, DO, FACAAI

Advisor: Biomarin, CSL Behring, Ionis, Kalvista, Takeda

Consultant: Biocryst, Biomarin, CSL Behring, Ionis, Kalvista, Ono, Takeda

Independent Contractor: Kalvista, Phavaris

Researcher: Astria, Biomarin, CSL Behring, GlaxoSmithKline, Ionis, Kalvista, Phavaris, Takeda

Speaker: Biomarin, CSL Behring, Kalvista, Regeneron, Takeda

 

This podcast miniseries is supported by a grant from Takeda.